CMap Candidate Details

Structure:
CMap ID: C26645
Pert ID: BRD-K76210423
Compound Name: resiquimod
Targets: TLR7; TLR8
MoA: Toll-like receptor agonist
SMILES: CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O
InchiKey: BXNMTOQRYBFHNZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127362 BRD-K76210423 A375 3.33 uM 24 h -0.19 -0.78 0.0 0.27 0.94 0.3
127398 BRD-K76210423 A549 3.33 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.1
127436 BRD-K76210423 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127617 BRD-K76210423 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127653 BRD-K76210423 THP1 10 uM 24 h -0.26 -1.08 0.29 -0.31 -1.06 0.72
127698 BRD-K76210423 YAPC 10 uM 24 h 0.0 0.0 0.0 0.23 0.82 0.1
135374 BRD-K76210423 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135413 BRD-K76210423 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135444 BRD-K76210423 MCF10A 2.22 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
135478 BRD-K76210423 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).