CMap Candidate Details

Structure:
CMap ID: C26647
Pert ID: BRD-K76211160
Compound Name: BRD-K76211160
Targets: CYP11B2
MoA: Cytochrome P450 inhibitor
SMILES: Fc1ccc(cc1)C(=O)Nc2cccnc2
InchiKey: AILCVPMYLXWTCO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
13865 BRD-K76211160 A375 10 uM 24 h -0.24 -1.02 0.17 0.0 0.0 0.0
14164 BRD-K76211160 A549 10 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
14517 BRD-K76211160 HA1E 10 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
14887 BRD-K76211160 HCC515 10 uM 6 h -0.21 -0.87 0.02 0.0 0.0 0.0
15128 BRD-K76211160 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
15528 BRD-K76211160 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
15665 BRD-K76211160 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
16062 BRD-K76211160 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).