CMap Candidate Details

Structure:
CMap ID: C26822
Pert ID: BRD-K76698671
Compound Name: HNHA
Targets: HDAC1
MoA: HDAC inhibitor
SMILES: ONC(=O)CCCCCCSc1ccc2ccccc2c1
InchiKey: KPNNXHVGOKRBEF-UHFFFAOYSA-N
Compound Aliases: hnha

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33730 BRD-K76698671 A375 10 uM 6 h -0.25 -1.05 0.23 0.0 0.0 0.0
33837 BRD-K76698671 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34173 BRD-K76698671 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34416 BRD-K76698671 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34680 BRD-K76698671 HCC515 10 uM 6 h 0.23 0.98 0.09 0.45 1.58 2.35
34954 BRD-K76698671 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35197 BRD-K76698671 HT29 10 uM 6 h -0.29 -1.21 0.57 0.0 0.0 0.0
35494 BRD-K76698671 MCF??7.00 10 uM 6 h -0.24 -0.99 0.13 0.0 0.0 0.0
35616 BRD-K76698671 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35836 BRD-K76698671 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35996 BRD-K76698671 PC3 10 uM 24 h 0.0 0.0 0.0 0.33 1.17 0.93
36345 BRD-K76698671 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36641 BRD-K76698671 SKB 10 uM 24 h 0.32 1.35 0.96 0.31 1.1 0.7
36865 BRD-K76698671 VCAP 10 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.28
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).