CMap Candidate Details

Structure:
CMap ID: C26870
Pert ID: BRD-K76840893
Compound Name: RS-17053
Targets: ADRA1A
MoA: Adrenergic receptor antagonist
SMILES: CC(C)(Cc1c[nH]c2ccc(Cl)cc12)NCCOc1ccccc1OCC1CC1
InchiKey: XLZHXAXXJVKTFM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1778 BRD-K76840893 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.89 0.27
1971 BRD-K76840893 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
2215 BRD-K76840893 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2519 BRD-K76840893 VCAP 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.47
41842 BRD-K76840893 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41979 BRD-K76840893 A549 10 uM 24 h 0.21 0.88 0.01 0.38 1.36 1.72
42474 BRD-K76840893 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42784 BRD-K76840893 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43077 BRD-K76840893 HT29 10 uM 6 h 0.22 0.9 0.02 0.0 0.0 0.0
43235 BRD-K76840893 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43951 BRD-K76840893 PHH 10 uM 24 h 0.26 1.09 0.22 0.0 0.0 0.0
44203 BRD-K76840893 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99488 BRD-K76840893 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).