CMap Candidate Details

Structure:
CMap ID: C26927
Pert ID: BRD-K76969307
Compound Name: CG-930
Targets: MAPK8
MoA: JNK inhibitor
SMILES: C1COC[C@@H]1N2C3=NC(=NC=C3N=C2NC4=C(C=C(C=C4F)F)F)NC5CCC(CC5)O
InchiKey: IBGLGMOPHJQDJB-ROKHWSDSSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
94415 BRD-K76969307 A375 3.33 uM 24 h 0.31 1.29 0.65 0.0 0.0 0.0
94447 BRD-K76969307 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94483 BRD-K76969307 ASC 10 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.29
94551 BRD-K76969307 CD34 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94598 BRD-K76969307 HCC515 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94642 BRD-K76969307 HEK293 10 uM 24 h 0.0 0.0 0.0 0.36 1.27 1.34
94692 BRD-K76969307 HELA 3.33 uM 24 h 0.24 0.99 0.1 0.0 0.0 0.0
94746 BRD-K76969307 HME1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94793 BRD-K76969307 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94838 BRD-K76969307 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.07
94891 BRD-K76969307 JURKAT 10 uM 24 h 0.21 0.89 0.02 0.23 0.81 0.08
94937 BRD-K76969307 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.3 1.08 0.64
94976 BRD-K76969307 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.14
95017 BRD-K76969307 NEU 10 uM 24 h -0.26 -1.09 0.33 0.0 0.0 0.0
95077 BRD-K76969307 NPC 0.37 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
95118 BRD-K76969307 PC3 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95164 BRD-K76969307 SHSY5Y 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95235 BRD-K76969307 SKL 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95274 BRD-K76969307 THP1 10 uM 24 h 0.18 0.74 0.0 -0.28 -0.94 0.39
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).