CMap Candidate Details

Structure:
CMap ID: C27044
Pert ID: BRD-K77390737
Compound Name: xanthohumol
Targets: VCP
MoA: ATPase inhibitor
SMILES: COc1cc(O)c(CC=C(C)C)c(O)c1C(=O)/C=C/c2ccc(O)cc2
InchiKey: ORXQGKIUCDPEAJ-YRNVUSSQSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33666 BRD-K77390737 A375 10 uM 6 h 0.23 0.95 0.07 0.27 0.96 0.34
33841 BRD-K77390737 A549 10 uM 24 h 0.28 1.15 0.34 -0.58 -1.96 15.65
34177 BRD-K77390737 ASC 10 uM 24 h 0.0 0.0 0.0 -0.53 -1.78 15.65
34420 BRD-K77390737 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34684 BRD-K77390737 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34959 BRD-K77390737 HEPG2 10 uM 6 h 0.22 0.93 0.05 -0.4 -1.36 2.02
35201 BRD-K77390737 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35446 BRD-K77390737 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35619 BRD-K77390737 NEU 10 uM 24 h -0.19 -0.79 0.0 0.27 0.95 0.31
35839 BRD-K77390737 NPC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
35998 BRD-K77390737 PC3 10 uM 24 h 0.25 1.05 0.18 -0.52 -1.74 15.65
36349 BRD-K77390737 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36646 BRD-K77390737 SKB 10 uM 24 h -0.2 -0.83 0.0 -0.34 -1.13 1.0
36869 BRD-K77390737 VCAP 10 uM 24 h 0.25 1.03 0.14 -0.36 -1.22 1.25
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).