CMap Candidate Details

Structure:
CMap ID: C27046
Pert ID: BRD-K77396579
Compound Name: NVP-DPP728
Targets: DPP4
MoA: Dipeptidyl peptidase inhibitor
SMILES: O=C(CNCCNc1ccc(cn1)C#N)N1CCC[C@H]1C#N
InchiKey: VFFZWMWTUSXDCB-ZDUSSCGKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96388 BRD-K77396579 PC3 10 uM 24 h 0.24 1.02 0.13 0.3 1.07 0.63
127074 BRD-K77396579 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127107 BRD-K77396579 HELA 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127143 BRD-K77396579 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127214 BRD-K77396579 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
127286 BRD-K77396579 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135019 BRD-K77396579 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135051 BRD-K77396579 A549 0.08 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.48
135089 BRD-K77396579 HA1E 2.22 uM 24 h 0.24 1.0 0.11 0.0 0.0 0.0
135179 BRD-K77396579 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135212 BRD-K77396579 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135275 BRD-K77396579 MDAMB231 0.25 uM 24 h 0.21 0.89 0.02 -0.31 -1.04 0.65
135330 BRD-K77396579 YAPC 0.01 uM 24 h 0.0 0.0 0.0 -0.42 -1.43 15.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).