CMap Candidate Details

Structure:
CMap ID: C27062
Pert ID: BRD-K77432048
Compound Name: BRD-K77432048
Targets: --
MoA: --
SMILES: COc1ccc(Nc2nc(N)nc(CN3CCCCC3)n2)cc1
InchiKey: PVHJDJWPRZUURH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8985 BRD-K77432048 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9507 BRD-K77432048 AGS 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.82
9811 BRD-K77432048 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10082 BRD-K77432048 HA1E 10 uM 6 h 0.0 0.0 0.0 0.34 1.2 1.12
10264 BRD-K77432048 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10593 BRD-K77432048 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10848 BRD-K77432048 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11014 BRD-K77432048 HT29 10 uM 24 h -0.26 -1.09 0.33 -0.2 -0.68 0.02
12130 BRD-K77432048 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12445 BRD-K77432048 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12949 BRD-K77432048 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13359 BRD-K77432048 U937 10 uM 6 h 0.21 0.89 0.02 0.0 0.0 0.0
88125 BRD-K77432048 VCAP 10 uM 6 h 0.0 0.0 0.0 0.24 0.86 0.15
90573 BRD-K77432048 A549 0.125 uM 6 h 0.0 0.0 0.0 -0.34 -1.13 0.98
90585 BRD-K77432048 MCF??7.00 0.125 uM 24 h 0.26 1.08 0.22 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).