CMap Candidate Details

Structure:
CMap ID: C27094
Pert ID: BRD-K77554836
Compound Name: triamcinolone
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@@H](O)[C@]2(O)C(=O)CO
InchiKey: GFNANZIMVAIWHM-OBYCQNJPSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4141 BRD-K77554836 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4487 BRD-K77554836 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.23 1.28
4823 BRD-K77554836 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5126 BRD-K77554836 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44446 BRD-K77554836 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44620 BRD-K77554836 A549 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.63
45029 BRD-K77554836 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45579 BRD-K77554836 HT29 10 uM 6 h 0.0 0.0 0.0 0.29 1.03 0.52
45721 BRD-K77554836 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.92
46142 BRD-K77554836 NPC 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.3 1.6
46458 BRD-K77554836 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46782 BRD-K77554836 SKB 10 uM 24 h -0.27 -1.14 0.42 0.0 0.0 0.0
91255 BRD-K77554836 HUH7 8 uM 72 h 0.0 0.0 0.0 0.28 0.98 0.37
99495 BRD-K77554836 U2OS 4 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).