CMap Candidate Details

Structure:
CMap ID: C27136
Pert ID: BRD-K77690805
Compound Name: BRD-K77690805
Targets: PKM
MoA: Pyruvate kinase isozyme activator
SMILES: Cc1ccc(NS(=O)(=O)c2ccc3NC(=O)CCc3c2)cc1C
InchiKey: SNFROMRRGGKYTF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
13867 BRD-K77690805 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
22160 BRD-K77690805 A549 10 uM 24 h -0.23 -0.96 0.1 -0.3 -1.01 0.56
22566 BRD-K77690805 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22849 BRD-K77690805 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23151 BRD-K77690805 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23440 BRD-K77690805 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23757 BRD-K77690805 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.23 1.25
24043 BRD-K77690805 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24213 BRD-K77690805 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115183 BRD-K77690805 U2OS 20 uM 6 h 0.3 1.24 0.53 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).