CMap Candidate Details

Structure:
CMap ID: C27185
Pert ID: BRD-K77830450
Compound Name: forskolin
Targets: ADCY2
MoA: Adenylyl cyclase activator
SMILES: CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C
InchiKey: OHCQJHSOBUTRHG-ZYIXGEAZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5365 BRD-K77830450 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5686 BRD-K77830450 HCC515 10 uM 24 h -0.28 -1.16 0.47 0.0 0.0 0.0
5954 BRD-K77830450 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.85
6217 BRD-K77830450 PC3 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.25
6590 BRD-K77830450 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44447 BRD-K77830450 A375 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.81 0.13
44621 BRD-K77830450 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45031 BRD-K77830450 ASC 10 uM 24 h -0.26 -1.09 0.32 0.0 0.0 0.0
45580 BRD-K77830450 HT29 10 uM 6 h -0.22 -0.91 0.05 -0.51 -1.72 15.65
45848 BRD-K77830450 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46144 BRD-K77830450 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46460 BRD-K77830450 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46784 BRD-K77830450 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98935 BRD-K77830450 NEU 10 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).