CMap Candidate Details

Structure:
CMap ID: C27201
Pert ID: BRD-K77876724
Compound Name: YL-51
Targets: --
MoA: --
SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)CCNC(C)=O)C(C)C)C(=O)N[C@]1(C)CCCC=C/CCC[C@@](C)(NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCSC)NC1=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
InchiKey: PDGWCICOBAAHML-VAFZWBSWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49890 BRD-K77876724 A375 10 uM 6 h 0.0 0.0 0.0 0.27 0.97 0.35
50051 BRD-K77876724 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50236 BRD-K77876724 HA1E 10 uM 6 h 0.26 1.07 0.2 -0.28 -0.94 0.38
50586 BRD-K77876724 HT29 10 uM 6 h 0.0 0.0 0.0 0.24 0.85 0.15
50780 BRD-K77876724 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50951 BRD-K77876724 PC3 10 uM 6 h 0.0 0.0 0.0 0.31 1.1 0.68
51180 BRD-K77876724 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.83 0.16
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).