CMap Candidate Details

Structure:
CMap ID: C27246
Pert ID: BRD-K77987635
Compound Name: BRD-K77987635
Targets: --
MoA: --
SMILES: C[C@H](CO)N1C[C@H](C)[C@@H](CN(C)CC2CC2)Oc3ccc(NC(=O)Nc4cccc5ccccc45)cc3CC1=O
InchiKey: XMNRWSIHUYWWSG-IABYTQIASA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
30247 BRD-K77987635 A549 10 uM 6 h -0.23 -0.94 0.08 0.33 1.15 0.9
30554 BRD-K77987635 ASC 10 uM 24 h 0.0 0.0 0.0 0.21 0.75 0.04
30842 BRD-K77987635 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31449 BRD-K77987635 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
32528 BRD-K77987635 NPC 10 uM 24 h -0.29 -1.23 0.62 -0.33 -1.12 0.95
33138 BRD-K77987635 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
82711 BRD-K77987635 A375 10 uM 24 h -0.23 -0.96 0.1 -0.28 -0.93 0.35
82992 BRD-K77987635 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
83180 BRD-K77987635 HT29 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.79 0.11
83268 BRD-K77987635 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.83
83353 BRD-K77987635 PC3 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
88107 BRD-K77987635 VCAP 30 uM 24 h 0.24 0.99 0.1 -0.25 -0.86 0.21
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).