CMap Candidate Details

Structure:
CMap ID: C27264
Pert ID: BRD-K78055238
Compound Name: LY-2090314
Targets: --
MoA: --
SMILES: Fc1cc2CN(CCn3cc(C4=C(C(=O)NC4=O)c4cnc5ccccn45)c(c1)c23)C(=O)N1CCCCC1
InchiKey: HRJWTAWVFDCTGO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127030 BRD-K78055238 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127113 BRD-K78055238 HELA 1.11 uM 24 h 0.32 1.33 0.84 0.0 0.0 0.0
127149 BRD-K78055238 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127219 BRD-K78055238 MCF??7.00 3.33 uM 24 h 0.24 1.0 0.11 0.0 0.0 0.0
127252 BRD-K78055238 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127290 BRD-K78055238 THP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127324 BRD-K78055238 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135056 BRD-K78055238 A549 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135091 BRD-K78055238 HA1E 0.25 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.12
135113 BRD-K78055238 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135183 BRD-K78055238 JURKAT 0.08 uM 24 h 0.27 1.13 0.3 0.31 1.09 0.67
135216 BRD-K78055238 MCF10A 0.74 uM 24 h 0.25 1.03 0.13 0.4 1.42 2.19
135281 BRD-K78055238 MDAMB231 0.25 uM 24 h 0.25 1.03 0.13 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).