CMap Candidate Details

Structure:
CMap ID: C02730
Pert ID: BRD-K01039503
Compound Name: sofalcone
Targets: CBR1
MoA: Mucus protecting agent
SMILES: CC(C)=CCOc1ccc(C=CC(=O)c2ccc(OCC=C(C)C)cc2OCC(O)=O)cc1
InchiKey: GFWRVVCDTLRWPK-KPKJPENVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122831 BRD-K01039503 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122858 BRD-K01039503 HA1E 10 uM 24 h 0.22 0.92 0.04 -0.36 -1.21 1.24
122889 BRD-K01039503 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.23
122937 BRD-K01039503 HELA 10 uM 24 h -0.3 -1.26 0.71 0.0 0.0 0.0
122969 BRD-K01039503 HT29 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.48
123014 BRD-K01039503 JURKAT 3.33 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
123060 BRD-K01039503 MCF10A 10 uM 24 h 0.3 1.24 0.52 0.26 0.94 0.28
123074 BRD-K01039503 MCF??7.00 10 uM 24 h 0.23 0.97 0.08 -0.3 -1.01 0.56
123103 BRD-K01039503 MDAMB231 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123145 BRD-K01039503 PC3 10 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.35
123175 BRD-K01039503 THP1 0.37 uM 24 h -0.25 -1.04 0.22 -0.39 -1.3 1.58
131240 BRD-K01039503 A549 0.25 uM 24 h -0.27 -1.12 0.39 -0.27 -0.9 0.28
131351 BRD-K01039503 HUVEC 0.08 uM 24 h 0.22 0.92 0.04 -0.31 -1.03 0.62
131490 BRD-K01039503 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).