CMap Candidate Details

Structure:
CMap ID: C27367
Pert ID: BRD-K78373679
Compound Name: Ro-3306
Targets: CDK1
MoA: CDK inhibitor
SMILES: O=C1N=C(NCc2cccs2)SC1=C/c1ccc2ncccc2c1
InchiKey: XOLMRFUGOINFDQ-YBEGLDIGSA-N
Compound Aliases: RO-3306

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49892 BRD-K78373679 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50054 BRD-K78373679 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50238 BRD-K78373679 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50411 BRD-K78373679 HCC515 10 uM 6 h 0.0 0.0 0.0 0.31 1.11 0.72
50588 BRD-K78373679 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50781 BRD-K78373679 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51181 BRD-K78373679 VCAP 10 uM 6 h 0.22 0.9 0.02 0.0 0.0 0.0
96802 BRD-K78373679 PC3 3.33 uM 24 h -0.25 -1.03 0.2 -0.29 -0.98 0.49
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).