CMap Candidate Details

Structure:
CMap ID: C27398
Pert ID: BRD-K78485176
Compound Name: olmesartan-medoxomil
Targets: AGTR1
MoA: Angiotensin receptor antagonist
SMILES: CCCc1nc(C(C)(C)O)c(C(=O)OCc2oc(=O)oc2C)n1Cc1ccc(cc1)-c1ccccc1-c1nn[nH]n1
InchiKey: UQGKUQLKSCSZGY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5803 BRD-K78485176 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5956 BRD-K78485176 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6591 BRD-K78485176 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37740 BRD-K78485176 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38556 BRD-K78485176 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91098 BRD-K78485176 HUH7 6.66 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
95421 BRD-K78485176 U2OS 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
127032 BRD-K78485176 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127052 BRD-K78485176 HA1E 0.04 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
127116 BRD-K78485176 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127151 BRD-K78485176 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127220 BRD-K78485176 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127254 BRD-K78485176 PC3 0.04 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
127292 BRD-K78485176 THP1 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127327 BRD-K78485176 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135059 BRD-K78485176 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135116 BRD-K78485176 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135186 BRD-K78485176 JURKAT 0.08 uM 24 h 0.25 1.04 0.16 0.37 1.3 1.59
135218 BRD-K78485176 MCF10A 0.03 uM 24 h 0.27 1.11 0.26 0.0 0.0 0.0
135284 BRD-K78485176 MDAMB231 0.08 uM 24 h 0.32 1.32 0.79 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).