CMap Candidate Details

Structure:
CMap ID: C27493
Pert ID: BRD-K78790801
Compound Name: KIN001-269
Targets: --
MoA: --
SMILES: CC1CCN(CC1)C2=C(C=CC(=C2)N3CCN(CC3)C)NC(=O)C4=CC(=CN4)C#N
InchiKey: DXPSQKSTVIVZLV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
94422 BRD-K78790801 A375 0.12 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
94456 BRD-K78790801 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94517 BRD-K78790801 ASC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94563 BRD-K78790801 CD34 3.33 uM 24 h -0.19 -0.78 0.0 0.0 0.0 0.0
94609 BRD-K78790801 HCC515 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94651 BRD-K78790801 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94701 BRD-K78790801 HELA 1.11 uM 24 h 0.24 1.01 0.12 -0.26 -0.89 0.26
94758 BRD-K78790801 HME1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94800 BRD-K78790801 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94850 BRD-K78790801 HUVEC 10 uM 24 h 0.3 1.26 0.57 0.0 0.0 0.0
94900 BRD-K78790801 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
94946 BRD-K78790801 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.34
94983 BRD-K78790801 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95028 BRD-K78790801 NEU 0.04 uM 24 h 0.31 1.3 0.73 0.31 1.09 0.67
95094 BRD-K78790801 NPC 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95126 BRD-K78790801 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95176 BRD-K78790801 SHSY5Y 1.11 uM 24 h 0.27 1.13 0.28 0.0 0.0 0.0
95216 BRD-K78790801 SKL 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95285 BRD-K78790801 THP1 0.04 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.72
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).