CMap Candidate Details

Structure:
CMap ID: C00275
Pert ID: BRD-A10903566
Compound Name: imiloxan
Targets: ADRA2A; ADRA2B
MoA: Adrenergic receptor antagonist
SMILES: CCn1ccnc1CC1COc2ccccc2O1
InchiKey: UXABARREKCJULM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
7505 BRD-A10903566 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8546 BRD-A10903566 VCAP 10 uM 24 h 0.24 1.01 0.12 -0.25 -0.84 0.18
121163 BRD-A10903566 A375 0.125 uM 24 h 0.17 0.7 0.0 0.0 0.0 0.0
121199 BRD-A10903566 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121233 BRD-A10903566 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121354 BRD-A10903566 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129280 BRD-A10903566 HELA 2.22 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
129312 BRD-A10903566 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129345 BRD-A10903566 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129358 BRD-A10903566 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).