CMap Candidate Details
Structure:
| CMap ID: | C02750 |
| Pert ID: | BRD-K01109406 |
| Compound Name: | nitisinone |
| Targets: | HPD |
| MoA: | Hydroxyphenylpyruvate dioxygenase inhibitor |
| SMILES: | [O-][N+](=O)c1cc(ccc1C(=O)C1C(=O)CCCC1=O)C(F)(F)F |
| InchiKey: | OUBCNLGXQFSTLU-UHFFFAOYSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 96486 | BRD-K01109406 | A375 | 10 uM | 24 h | 0.2 | 0.84 | 0.0 | -0.29 | -0.98 | 0.47 |
| 96553 | BRD-K01109406 | PC3 | 10 uM | 24 h | -0.27 | -1.13 | 0.41 | -0.3 | -1.0 | 0.52 |