CMap Candidate Details

Structure:
CMap ID: C27552
Pert ID: BRD-K78959463
Compound Name: FPL-64176
Targets: CACNA1C
MoA: Calcium channel activator
SMILES: COC(=O)c1c(C)[nH]c(C)c1C(=O)c1ccccc1Cc1ccccc1
InchiKey: MDMWHKZANMNXTF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8988 BRD-K78959463 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9514 BRD-K78959463 AGS 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.32 1.71
9819 BRD-K78959463 H1299 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.79 0.11
10083 BRD-K78959463 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.2 -0.67 0.01
10260 BRD-K78959463 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12137 BRD-K78959463 NCIH596 10 uM 6 h -0.22 -0.92 0.06 -0.29 -0.96 0.44
12441 BRD-K78959463 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
13365 BRD-K78959463 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13684 BRD-K78959463 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44623 BRD-K78959463 A549 10 uM 24 h 0.0 0.0 0.0 0.32 1.12 0.79
45036 BRD-K78959463 ASC 10 uM 24 h 0.19 0.79 0.0 0.28 0.98 0.37
45325 BRD-K78959463 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45583 BRD-K78959463 HT29 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.83 0.17
45850 BRD-K78959463 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.88 0.26
46148 BRD-K78959463 NPC 10 uM 24 h -0.26 -1.09 0.32 0.25 0.87 0.18
46789 BRD-K78959463 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).