CMap Candidate Details

Structure:
CMap ID: C27595
Pert ID: BRD-K79102359
Compound Name: idalopirdine
Targets: HTR6
MoA: Serotonin receptor antagonist
SMILES: FC(F)C(F)(F)COc1cccc(CNCCc2c[nH]c3cc(F)ccc23)c1
InchiKey: YBAWYTYNMZWMMJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127372 BRD-K79102359 A375 10 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
127405 BRD-K79102359 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127449 BRD-K79102359 HA1E 10 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.14
127477 BRD-K79102359 HELA 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
127492 BRD-K79102359 HT29 0.04 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
127539 BRD-K79102359 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127566 BRD-K79102359 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127586 BRD-K79102359 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
127627 BRD-K79102359 PC3 10 uM 24 h 0.0 0.0 0.0 0.35 1.25 1.29
127662 BRD-K79102359 THP1 10 uM 24 h -0.3 -1.24 0.67 -0.23 -0.78 0.09
127712 BRD-K79102359 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).