CMap Candidate Details

Structure:
CMap ID: C27642
Pert ID: BRD-K79239947
Compound Name: PF-573228
Targets: --
MoA: --
SMILES: CS(=O)(=O)c1cccc(CNc2nc(Nc3ccc4NC(=O)CCc4c3)ncc2C(F)(F)F)c1
InchiKey: HESLKTSGTIBHJU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
94487 BRD-K79239947 ASC 10 uM 24 h 0.0 0.0 0.0 -0.18 -0.6 0.0
94556 BRD-K79239947 CD34 10 uM 24 h -0.32 -1.33 0.89 -0.29 -0.97 0.45
94602 BRD-K79239947 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
94647 BRD-K79239947 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94696 BRD-K79239947 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94751 BRD-K79239947 HME1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94843 BRD-K79239947 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94896 BRD-K79239947 JURKAT 10 uM 24 h 0.24 1.02 0.12 0.0 0.0 0.0
94940 BRD-K79239947 MCF10A 10 uM 24 h 0.19 0.78 0.0 0.0 0.0 0.0
95021 BRD-K79239947 NEU 10 uM 24 h 0.34 1.41 1.03 0.0 0.0 0.0
95081 BRD-K79239947 NPC 10 uM 24 h 0.33 1.38 0.97 0.0 0.0 0.0
95169 BRD-K79239947 SHSY5Y 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95213 BRD-K79239947 SKL 10 uM 24 h 0.0 0.0 0.0 0.37 1.3 1.49
95279 BRD-K79239947 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117013 BRD-K79239947 A375 10 uM 24 h -0.18 -0.76 0.0 0.0 0.0 0.0
117050 BRD-K79239947 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117090 BRD-K79239947 HA1E 10 uM 24 h 0.27 1.14 0.32 0.0 0.0 0.0
117179 BRD-K79239947 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.21 0.73 0.03
117224 BRD-K79239947 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117264 BRD-K79239947 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117298 BRD-K79239947 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).