CMap Candidate Details

Structure:
CMap ID: C27684
Pert ID: BRD-K79366068
Compound Name: PSB-069
Targets: ENTPD1; ENTPD2; ENTPD3
MoA: NTPDase inhibitor
SMILES: Nc1c(cc(Nc2ccc(Cl)cc2)c3C(=O)c4ccccc4C(=O)c13)S(=O)(=O)O
InchiKey: MHSMKEQLFFWYOS-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5478 BRD-K79366068 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5687 BRD-K79366068 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5957 BRD-K79366068 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6056 BRD-K79366068 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6112 BRD-K79366068 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6298 BRD-K79366068 PC3 10 uM 6 h -0.18 -0.75 0.0 0.0 0.0 0.0
6592 BRD-K79366068 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37190 BRD-K79366068 A375 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.57
37310 BRD-K79366068 A549 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
37742 BRD-K79366068 ASC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.35
38558 BRD-K79366068 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38781 BRD-K79366068 PHH 10 uM 24 h 0.22 0.9 0.03 0.0 0.0 0.0
39007 BRD-K79366068 SKB 10 uM 24 h -0.24 -0.98 0.13 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).