CMap Candidate Details

Structure:
CMap ID: C00277
Pert ID: BRD-A10967948
Compound Name: granisetron
Targets: HTR3A
MoA: Serotonin receptor antagonist
SMILES: CN1C2CCCC1CC(C2)NC(=O)c1nn(C)c2ccccc12
InchiKey: MFWNKCLOYSRHCJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121164 BRD-A10967948 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121200 BRD-A10967948 A549 1.11 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.87
121234 BRD-A10967948 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121326 BRD-A10967948 PC3 0.04 uM 24 h -0.27 -1.12 0.39 0.0 0.0 0.0
129267 BRD-A10967948 HELA 2.22 uM 24 h -0.28 -1.16 0.47 0.0 0.0 0.0
129313 BRD-A10967948 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129346 BRD-A10967948 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129384 BRD-A10967948 YAPC 0.03 uM 24 h -0.24 -1.0 0.15 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).