CMap Candidate Details

Structure:
CMap ID: C27747
Pert ID: BRD-K79595931
Compound Name: bavisant
Targets: HRH3
MoA: Histamine receptor antagonist
SMILES: O=C(N1CCN(CC1)C1CC1)c1ccc(CN2CCOCC2)cc1
InchiKey: BGBVSGSIXIIREO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127057 BRD-K79595931 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127122 BRD-K79595931 HELA 3.33 uM 24 h 0.2 0.85 0.01 -0.25 -0.86 0.2
127157 BRD-K79595931 HT29 3.33 uM 24 h 0.28 1.15 0.32 0.0 0.0 0.0
127192 BRD-K79595931 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127222 BRD-K79595931 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 -0.19 -0.65 0.01
127259 BRD-K79595931 PC3 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127298 BRD-K79595931 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127331 BRD-K79595931 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.34
135022 BRD-K79595931 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135065 BRD-K79595931 A549 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135121 BRD-K79595931 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135191 BRD-K79595931 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135291 BRD-K79595931 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).