CMap Candidate Details

Structure:
CMap ID: C27827
Pert ID: BRD-K79905821
Compound Name: gabazine
Targets: GABRA1
MoA: GABA receptor antagonist
SMILES: COc1ccc(cc1)-c1ccc(=N)n(CCCC(O)=O)n1
InchiKey: ACVGNKYJVGNLIL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6904 BRD-K79905821 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7026 BRD-K79905821 A549 10 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
7355 BRD-K79905821 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
7715 BRD-K79905821 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.17 -0.56 0.0
8025 BRD-K79905821 HT29 10 uM 6 h 0.0 0.0 0.0 -0.4 -1.36 2.02
8111 BRD-K79905821 MCF??7.00 10 uM 24 h 0.27 1.11 0.25 0.31 1.1 0.7
8845 BRD-K79905821 VCAP 10 uM 6 h 0.22 0.91 0.03 -0.35 -1.18 1.14
97237 BRD-K79905821 PC3 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.2
136395 BRD-K79905821 SHSY5Y 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).