CMap Candidate Details

Structure:
CMap ID: C27851
Pert ID: BRD-K79989959
Compound Name: nesbuvir
Targets: --
MoA: --
SMILES: CNC(=O)c1c(oc2cc(N(CCO)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1
InchiKey: WTDWVLJJJOTABN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127376 BRD-K79989959 A375 0.04 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
127453 BRD-K79989959 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.34
127480 BRD-K79989959 HELA 1.11 uM 24 h 0.0 0.0 0.0 0.39 1.38 2.17
127544 BRD-K79989959 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.12
127631 BRD-K79989959 PC3 0.04 uM 24 h 0.25 1.04 0.16 0.29 1.02 0.49
127717 BRD-K79989959 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135355 BRD-K79989959 A549 0.74 uM 24 h 0.16 0.65 0.0 -0.28 -0.95 0.4
135423 BRD-K79989959 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135457 BRD-K79989959 MCF10A 0.01 uM 24 h 0.29 1.23 0.49 -0.23 -0.78 0.09
135487 BRD-K79989959 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135512 BRD-K79989959 THP1 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).