CMap Candidate Details

Structure:
CMap ID: C27883
Pert ID: BRD-K80082640
Compound Name: otamixaban
Targets: F10
MoA: Coagulation factor inhibitor
SMILES: COC(=O)[C@H](Cc1cccc(c1)C(N)=N)[C@@H](C)NC(=O)c1ccc(cc1)-c1cc[n+]([O-])cc1
InchiKey: PFGVNLZDWRZPJW-OPAMFIHVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125576 BRD-K80082640 A375 0.04 uM 24 h 0.0 0.0 0.0 0.37 1.31 1.59
125672 BRD-K80082640 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125725 BRD-K80082640 HUVEC 0.37 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.1
125772 BRD-K80082640 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
125799 BRD-K80082640 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.25
125871 BRD-K80082640 PC3 0.37 uM 24 h -0.21 -0.88 0.03 0.27 0.95 0.31
125924 BRD-K80082640 YAPC 0.04 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
133661 BRD-K80082640 A549 0.03 uM 24 h -0.26 -1.09 0.33 0.2 0.71 0.02
133694 BRD-K80082640 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133728 BRD-K80082640 HEK293 0.01 uM 24 h 0.2 0.83 0.0 0.27 0.96 0.33
133793 BRD-K80082640 HT29 0.25 uM 24 h 0.0 0.0 0.0 -0.38 -1.28 1.45
133879 BRD-K80082640 MCF??7.00 2.22 uM 24 h 0.26 1.08 0.21 -0.32 -1.09 0.84
133908 BRD-K80082640 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.15
133973 BRD-K80082640 THP1 0.74 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.36
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).