CMap Candidate Details

Structure:
CMap ID: C27984
Pert ID: BRD-K80451230
Compound Name: zamifenacin
Targets: CHRM3
MoA: Acetylcholine receptor antagonist
SMILES: C(Cc1ccc2OCOc2c1)N1CCC[C@H](C1)OC(c1ccccc1)c1ccccc1
InchiKey: BDNFQGRSKSQXRI-XMMPIXPASA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6802 BRD-K80451230 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7028 BRD-K80451230 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7357 BRD-K80451230 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7716 BRD-K80451230 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7914 BRD-K80451230 HT29 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.28
8139 BRD-K80451230 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.24 0.83 0.12
90379 BRD-K80451230 PC3 3.33 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
90422 BRD-K80451230 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).