CMap Candidate Details

Structure:
CMap ID: C00028
Pert ID: BRD-A01145011
Compound Name: zebularine
Targets: DNMT1; CDA
MoA: DNA methyltransferase inhibitor
SMILES: OC[C@H]1O[C@H](C(O)[C@H]1O)n1cccnc1=O
InchiKey: RPQZTTQVRYEKCR-JJFBUQMESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8855 BRD-A01145011 A375 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9259 BRD-A01145011 AGS 12 uM 6 h 0.0 0.0 0.0 0.34 1.2 1.09
9562 BRD-A01145011 H1299 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9996 BRD-A01145011 HA1E 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10198 BRD-A01145011 HCC515 12 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
10376 BRD-A01145011 HCT116 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10644 BRD-A01145011 HEPG2 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11093 BRD-A01145011 HT29 12 uM 6 h 0.0 0.0 0.0 0.2 0.71 0.02
11312 BRD-A01145011 NCIH2073 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11633 BRD-A01145011 NCIH508 12 uM 6 h 0.0 0.0 0.0 0.22 0.78 0.07
12518 BRD-A01145011 PC3 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12638 BRD-A01145011 SW480 12 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.38
13121 BRD-A01145011 U937 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13410 BRD-A01145011 VCAP 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90535 BRD-A01145011 A549 4 uM 6 h -0.27 -1.14 0.42 0.29 1.04 0.55
90543 BRD-A01145011 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).