CMap Candidate Details

Structure:
CMap ID: C28026
Pert ID: BRD-K80608265
Compound Name: erteberel
Targets: ESR2
MoA: Estrogen receptor agonist
SMILES: Oc1ccc(cc1)[C@@H]1Oc2ccc(O)cc2[C@@H]2CCC[C@H]12
InchiKey: XIESSJVMWNJCGZ-VKJFTORMSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125977 BRD-K80608265 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125998 BRD-K80608265 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126070 BRD-K80608265 HUVEC 10 uM 24 h -0.21 -0.87 0.02 -0.37 -1.26 1.35
126111 BRD-K80608265 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126166 BRD-K80608265 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.39 1.39 2.17
126213 BRD-K80608265 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.45 15.35
126231 BRD-K80608265 MDAMB231 10 uM 24 h 0.32 1.33 0.84 0.0 0.0 0.0
126254 BRD-K80608265 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126284 BRD-K80608265 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133997 BRD-K80608265 A375 2.22 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.43
134085 BRD-K80608265 HEK293 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134137 BRD-K80608265 HELA 2.22 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
134174 BRD-K80608265 HT29 2.22 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
134305 BRD-K80608265 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).