CMap Candidate Details

Structure:
CMap ID: C28057
Pert ID: BRD-K80725632
Compound Name: lavendustin-c
Targets: EGFR; SRC; CAMK2A
MoA: EGFR inhibitor
SMILES: OC(=O)c1cc(NCc2cc(O)ccc2O)ccc1O
InchiKey: LULATDWLDJOKCX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33700 BRD-K80725632 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33843 BRD-K80725632 A549 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.48
34689 BRD-K80725632 HCC515 10 uM 6 h -0.24 -0.99 0.13 0.0 0.0 0.0
34967 BRD-K80725632 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35206 BRD-K80725632 HT29 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.87 0.24
35473 BRD-K80725632 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.3 1.07 0.63
35623 BRD-K80725632 NEU 10 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
35844 BRD-K80725632 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36001 BRD-K80725632 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36355 BRD-K80725632 PHH 10 uM 24 h 0.25 1.02 0.13 0.0 0.0 0.0
36653 BRD-K80725632 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36876 BRD-K80725632 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).