CMap Candidate Details

Structure:
CMap ID: C28065
Pert ID: BRD-K80738081
Compound Name: resveratrol
Targets: SIRT1; PTGS1; PTGS2
MoA: SIRT activator; Cytochrome P450 inhibitor
SMILES: Oc1ccc(cc1)C=Cc1cc(O)cc(O)c1
InchiKey: LUKBXSAWLPMMSZ-OWOJBTEDSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9517 BRD-K80738081 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11020 BRD-K80738081 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11583 BRD-K80738081 NCIH2073 10 uM 6 h 0.0 0.0 0.0 -0.45 -1.53 15.35
11846 BRD-K80738081 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12142 BRD-K80738081 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23158 BRD-K80738081 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24218 BRD-K80738081 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87881 BRD-K80738081 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93687 BRD-K80738081 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93729 BRD-K80738081 CD34 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
93804 BRD-K80738081 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93854 BRD-K80738081 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.18 -0.59 0.0
93997 BRD-K80738081 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94119 BRD-K80738081 NEU 0.04 uM 24 h 0.23 0.98 0.09 0.0 0.0 0.0
94144 BRD-K80738081 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94253 BRD-K80738081 SHSY5Y 0.12 uM 24 h 0.28 1.15 0.34 0.0 0.0 0.0
94304 BRD-K80738081 SKL 10 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.23
94348 BRD-K80738081 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95782 BRD-K80738081 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95934 BRD-K80738081 YAPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
119722 BRD-K80738081 JURKAT 0.125 uM 24 h -0.2 -0.84 0.01 0.0 0.0 0.0
121169 BRD-K80738081 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121239 BRD-K80738081 HA1E 10 uM 24 h -0.24 -1.01 0.16 0.0 0.0 0.0
121256 BRD-K80738081 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121331 BRD-K80738081 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).