CMap Candidate Details

Structure:
CMap ID: C28163
Pert ID: BRD-K81062487
Compound Name: taurocholic-acid
Targets: CEL
MoA: Bile acid; G protein-coupled receptor agonist
SMILES: C[C@H](CCC(=O)NCCS(=O)(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
InchiKey: WBWWGRHZICKQGZ-IECFWMJSSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33612 BRD-K81062487 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33844 BRD-K81062487 A549 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
34183 BRD-K81062487 ASC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
34425 BRD-K81062487 HA1E 10 uM 6 h -0.31 -1.3 0.82 -0.29 -0.98 0.47
34690 BRD-K81062487 HCC515 10 uM 6 h -0.18 -0.76 0.0 -0.31 -1.05 0.7
34968 BRD-K81062487 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.23 0.83 0.12
35207 BRD-K81062487 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35416 BRD-K81062487 MCF??7.00 10 uM 6 h 0.23 0.97 0.08 0.0 0.0 0.0
36104 BRD-K81062487 PC3 10 uM 6 h 0.0 0.0 0.0 0.29 1.03 0.51
36356 BRD-K81062487 PHH 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
36654 BRD-K81062487 SKB 10 uM 24 h -0.22 -0.93 0.07 -0.28 -0.93 0.35
37005 BRD-K81062487 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91456 BRD-K81062487 HUH7 6.66 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
99094 BRD-K81062487 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99252 BRD-K81062487 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).