CMap Candidate Details

Structure:
CMap ID: C28182
Pert ID: BRD-K81128206
Compound Name: edrophonium
Targets: ACHE
MoA: Acetylcholinesterase inhibitor
SMILES: CC[N+](C)(C)c1cccc(O)c1
InchiKey: VWLHWLSRQJQWRG-UHFFFAOYSA-O
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
50058 BRD-K81128206 A549 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.76 0.07
50241 BRD-K81128206 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50591 BRD-K81128206 HT29 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.11 0.9
50688 BRD-K81128206 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
51070 BRD-K81128206 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.34 1.85
96740 BRD-K81128206 A375 10 uM 24 h -0.26 -1.06 0.26 -0.46 -1.55 15.35
96790 BRD-K81128206 PC3 10 uM 24 h 0.26 1.09 0.23 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).