CMap Candidate Details

Structure:
CMap ID: C28188
Pert ID: BRD-K81142122
Compound Name: STK-249718
Targets: --
MoA: --
SMILES: Cn1nc(nc2c(=O)n(C)c(=O)nc12)c3ccccn3
InchiKey: HDXJYJIPXWVRSM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33689 BRD-K81142122 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33933 BRD-K81142122 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34184 BRD-K81142122 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34426 BRD-K81142122 HA1E 10 uM 6 h 0.21 0.87 0.01 -0.45 -1.53 15.35
34691 BRD-K81142122 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35208 BRD-K81142122 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35461 BRD-K81142122 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35624 BRD-K81142122 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36105 BRD-K81142122 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37006 BRD-K81142122 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53475 BRD-K81142122 HEPG2 2.5 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53613 BRD-K81142122 HUH7 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53694 BRD-K81142122 PHH 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.96
115191 BRD-K81142122 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).