CMap Candidate Details

Structure:
CMap ID: C28221
Pert ID: BRD-K81258678
Compound Name: triptolide
Targets: --
MoA: --
SMILES: CC(C)[C@@]12O[C@@H]1[C@@H]1O[C@]11[C@]3(O[C@@H]3C[C@@H]3C4=C(CC[C@]13C)C(=O)OC4)[C@@H]2O
InchiKey: DFBIRQPKNDILPW-LKUXBXJISA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
126459 BRD-K81258678 HEK293 0.04 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.69
126563 BRD-K81258678 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134362 BRD-K81258678 A375 0.01 uM 24 h -0.27 -1.12 0.38 0.0 0.0 0.0
134384 BRD-K81258678 A549 0.01 uM 24 h 0.0 0.0 0.0 0.36 1.28 1.37
134413 BRD-K81258678 HA1E 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134442 BRD-K81258678 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134477 BRD-K81258678 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134526 BRD-K81258678 HUVEC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134552 BRD-K81258678 MCF10A 0.01 uM 24 h -0.17 -0.72 0.0 -0.38 -1.29 1.56
134579 BRD-K81258678 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134637 BRD-K81258678 PC3 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134662 BRD-K81258678 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.86
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).