CMap Candidate Details

Structure:
CMap ID: C28349
Pert ID: BRD-K81672972
Compound Name: dinoprost
Targets: PTGDR; PTGER1; PTGER3; PTGER4; PTGFR
MoA: Prostacyclin analog
SMILES: CCCCC[C@H](O)C=C[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC=C/CCCC(O)=O
InchiKey: PXGPLTODNUVGFL-YNNPMVKQSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90996 BRD-K81672972 HUH7 10 uM 72 h 0.0 0.0 0.0 -0.32 -1.08 0.8
124293 BRD-K81672972 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124311 BRD-K81672972 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124335 BRD-K81672972 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124394 BRD-K81672972 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.2
124473 BRD-K81672972 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124505 BRD-K81672972 PC3 0.04 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
124531 BRD-K81672972 YAPC 10 uM 24 h 0.28 1.16 0.36 0.25 0.9 0.21
132317 BRD-K81672972 A375 2.22 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
132345 BRD-K81672972 A549 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132453 BRD-K81672972 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132478 BRD-K81672972 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132513 BRD-K81672972 MCF??7.00 2.22 uM 24 h 0.27 1.14 0.31 0.34 1.21 1.15
132581 BRD-K81672972 THP1 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).