CMap Candidate Details

Structure:
CMap ID: C28359
Pert ID: BRD-K81709173
Compound Name: halcinonide
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)CC[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CCl
InchiKey: MUQNGPZZQDCDFT-JNQJZLCISA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1783 BRD-K81709173 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.49
1983 BRD-K81709173 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.76
2153 BRD-K81709173 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2637 BRD-K81709173 VCAP 10 uM 6 h 0.21 0.87 0.01 0.0 0.0 0.0
39191 BRD-K81709173 A375 10 uM 6 h -0.26 -1.07 0.27 -0.27 -0.92 0.33
39781 BRD-K81709173 ASC 10 uM 24 h 0.2 0.85 0.01 0.0 0.0 0.0
40338 BRD-K81709173 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40881 BRD-K81709173 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41200 BRD-K81709173 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41539 BRD-K81709173 SKB 10 uM 24 h -0.25 -1.04 0.22 -0.31 -1.06 0.73
95529 BRD-K81709173 A549 0.12 uM 6 h 0.28 1.18 0.38 -0.3 -1.01 0.57
95564 BRD-K81709173 MCF??7.00 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
95691 BRD-K81709173 U2OS 1.11 uM 6 h -0.23 -0.95 0.09 -0.28 -0.94 0.37
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).