CMap Candidate Details

Structure:
CMap ID: C28364
Pert ID: BRD-K81729199
Compound Name: AQ-RA741
Targets: CHRM2
MoA: Acetylcholine receptor antagonist
SMILES: CCN(CC)CCCCC1CCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc23)CC1
InchiKey: BCUGCHZRMKTPMU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1637 BRD-K81729199 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1984 BRD-K81729199 HCC515 10 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
2200 BRD-K81729199 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2688 BRD-K81729199 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39192 BRD-K81729199 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39348 BRD-K81729199 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39782 BRD-K81729199 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40074 BRD-K81729199 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.26 1.38
40339 BRD-K81729199 HT29 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.17 1.11
40642 BRD-K81729199 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.35 1.23 1.19
41201 BRD-K81729199 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41540 BRD-K81729199 SKB 10 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).