CMap Candidate Details

Structure:
CMap ID: C28380
Pert ID: BRD-K81795818
Compound Name: exherin
Targets: CDH2
MoA: Cadherin antagonist
SMILES: CC(C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(N)=O)NC(C)=O
InchiKey: FQVLRGLGWNWPSS-BXBUPLCLSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125578 BRD-K81795818 A375 10 uM 24 h -0.29 -1.19 0.53 -0.31 -1.04 0.66
125648 BRD-K81795818 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125695 BRD-K81795818 HT29 3.33 uM 24 h -0.24 -1.02 0.17 0.0 0.0 0.0
125729 BRD-K81795818 HUVEC 0.04 uM 24 h -0.26 -1.07 0.27 0.0 0.0 0.0
125775 BRD-K81795818 JURKAT 3.33 uM 24 h -0.37 -1.55 1.43 0.0 0.0 0.0
125825 BRD-K81795818 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125928 BRD-K81795818 YAPC 0.125 uM 24 h 0.0 0.0 0.0 -0.44 -1.48 15.35
133664 BRD-K81795818 A549 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133695 BRD-K81795818 HA1E 2.22 uM 24 h 0.0 0.0 0.0 -0.4 -1.34 1.85
133761 BRD-K81795818 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133853 BRD-K81795818 MCF10A 0.74 uM 24 h -0.26 -1.07 0.28 0.0 0.0 0.0
133911 BRD-K81795818 MDAMB231 0.03 uM 24 h -0.25 -1.04 0.22 0.0 0.0 0.0
133941 BRD-K81795818 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133975 BRD-K81795818 THP1 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).