CMap Candidate Details

Structure:
CMap ID: C28532
Pert ID: BRD-K82225283
Compound Name: BRD-K82225283
Targets: --
MoA: --
SMILES: O[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)O[N+]([O-])=O
InchiKey: YWXYYJSYQOXTPL-SLPGGIOYSA-N
Compound Aliases: isosorbide-mononitrate

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
52338 BRD-K82225283 PC3 10 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
126002 BRD-K82225283 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126030 BRD-K82225283 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126078 BRD-K82225283 HUVEC 0.04 uM 24 h 0.31 1.28 0.64 0.0 0.0 0.0
126123 BRD-K82225283 JURKAT 0.125 uM 24 h -0.26 -1.09 0.32 0.0 0.0 0.0
126176 BRD-K82225283 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126295 BRD-K82225283 THP1 10 uM 24 h 0.24 0.99 0.1 -0.25 -0.84 0.18
134004 BRD-K82225283 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134035 BRD-K82225283 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134097 BRD-K82225283 HEK293 0.74 uM 24 h -0.35 -1.46 1.43 0.0 0.0 0.0
134180 BRD-K82225283 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.37 1.3 1.49
134226 BRD-K82225283 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.29
134255 BRD-K82225283 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134310 BRD-K82225283 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).