CMap Candidate Details

Structure:
CMap ID: C28535
Pert ID: BRD-K82234479
Compound Name: tramiprosate
Targets: APP
MoA: Beta amyloid inhibitor
SMILES: NCCCS(O)(=O)=O
InchiKey: SNKZJIOFVMKAOJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
126075 BRD-K82234479 HUVEC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.63
126120 BRD-K82234479 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.41
126173 BRD-K82234479 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126216 BRD-K82234479 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.76
126292 BRD-K82234479 THP1 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126337 BRD-K82234479 YAPC 0.125 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.55
134002 BRD-K82234479 A375 0.08 uM 24 h 0.0 0.0 0.0 0.2 0.71 0.02
134033 BRD-K82234479 A549 0.08 uM 24 h 0.0 0.0 0.0 -0.24 -0.79 0.11
134062 BRD-K82234479 HA1E 0.25 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
134094 BRD-K82234479 HEK293 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134143 BRD-K82234479 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134178 BRD-K82234479 HT29 2.22 uM 24 h -0.23 -0.95 0.09 0.0 0.0 0.0
134252 BRD-K82234479 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.77
134285 BRD-K82234479 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).