CMap Candidate Details

Structure:
CMap ID: C28545
Pert ID: BRD-K82255054
Compound Name: propofol
Targets: GABRA1; GABRA2; GABRA3; GABRA4; GABRA5; GABRA6; GABRB1; GABRB2; GABRB3; GABRD; GABRE; GABRG1; GABRG2; GABRG3; GABRP; GABRQ
MoA: GABA receptor agonist
SMILES: CC(C)c1cccc(C(C)C)c1O
InchiKey: OLBCVFGFOZPWHH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4257 BRD-K82255054 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4496 BRD-K82255054 HCC515 10 uM 24 h -0.22 -0.91 0.05 0.22 0.79 0.07
4826 BRD-K82255054 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5130 BRD-K82255054 VCAP 10 uM 6 h 0.0 0.0 0.0 0.22 0.76 0.05
37193 BRD-K82255054 A375 10 uM 6 h -0.27 -1.13 0.4 0.36 1.29 1.46
37414 BRD-K82255054 A549 10 uM 6 h -0.2 -0.83 0.0 -0.3 -1.02 0.6
37747 BRD-K82255054 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37949 BRD-K82255054 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.24 0.85 0.15
38110 BRD-K82255054 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38224 BRD-K82255054 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38562 BRD-K82255054 NPC 10 uM 24 h 0.2 0.82 0.0 0.25 0.88 0.18
39012 BRD-K82255054 SKB 10 uM 24 h 0.21 0.88 0.01 0.32 1.12 0.76
91176 BRD-K82255054 HUH7 20 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).