CMap Candidate Details

Structure:
CMap ID: C28565
Pert ID: BRD-K82357231
Compound Name: desloratadine
Targets: HRH1
MoA: Histamine receptor antagonist
SMILES: Clc1ccc2c(CCc3cccnc3C2=C2CCNCC2)c1
InchiKey: JAUOIFJMECXRGI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24486 BRD-K82357231 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24614 BRD-K82357231 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24813 BRD-K82357231 HA1E 10 uM 6 h 0.0 0.0 0.0 0.25 0.88 0.19
24951 BRD-K82357231 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25194 BRD-K82357231 PC3 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.61
25535 BRD-K82357231 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
52202 BRD-K82357231 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91235 BRD-K82357231 HUH7 10 uM 72 h 0.0 0.0 0.0 0.31 1.1 0.7
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).