CMap Candidate Details

Structure:
CMap ID: C00286
Pert ID: BRD-A11135865
Compound Name: nor-binaltorphimine
Targets: OPRK1
MoA: Opioid receptor antagonist
SMILES: Oc1ccc2CC3N(CC4CC4)CCC5(C6Oc1c25)C3(O)Cc7c8CC9(O)C%10Cc%11ccc(O)c%12OC(c8[nH]c67)C9(CCN%10CC%13CC%13)c%12%11
InchiKey: APSUXPSYBJVPPS-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6618 BRD-A11135865 A375 10 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
7054 BRD-A11135865 A549 10 uM 6 h 0.0 0.0 0.0 0.3 1.06 0.61
7377 BRD-A11135865 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7506 BRD-A11135865 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7744 BRD-A11135865 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8263 BRD-A11135865 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8427 BRD-A11135865 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8548 BRD-A11135865 VCAP 10 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.12
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).