CMap Candidate Details

Structure:
CMap ID: C28600
Pert ID: BRD-K82467063
Compound Name: SB-271046
Targets: HTR6
MoA: Serotonin receptor antagonist
SMILES: COc1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1N1CCNCC1
InchiKey: LOCQRDBFWSXQQI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125963 BRD-K82467063 A375 10 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.13
125982 BRD-K82467063 A549 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
126003 BRD-K82467063 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126050 BRD-K82467063 HT29 10 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.51
126080 BRD-K82467063 HUVEC 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.21
126125 BRD-K82467063 JURKAT 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126178 BRD-K82467063 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126218 BRD-K82467063 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.62
126237 BRD-K82467063 MDAMB231 10 uM 24 h 0.19 0.79 0.0 0.37 1.3 1.58
126297 BRD-K82467063 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126339 BRD-K82467063 YAPC 10 uM 24 h -0.13 -0.56 0.0 0.24 0.84 0.13
134099 BRD-K82467063 HEK293 0.01 uM 24 h -0.22 -0.93 0.07 -0.38 -1.26 1.38
134146 BRD-K82467063 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.3 1.08 0.65
134286 BRD-K82467063 PC3 0.01 uM 24 h 0.25 1.06 0.19 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).