CMap Candidate Details

Structure:
CMap ID: C28607
Pert ID: BRD-K82484965
Compound Name: carmoxirole
Targets: DRD2
MoA: Dopamine receptor agonist
SMILES: OC(=O)c1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1
InchiKey: AFSOIHMEOKEZJF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3056 BRD-K82484965 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3398 BRD-K82484965 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.97 0.45
3547 BRD-K82484965 PC3 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.66
3873 BRD-K82484965 VCAP 10 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.56
39195 BRD-K82484965 A375 10 uM 6 h -0.22 -0.92 0.06 0.3 1.05 0.57
39500 BRD-K82484965 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39784 BRD-K82484965 ASC 10 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
40077 BRD-K82484965 HEPG2 10 uM 6 h 0.28 1.15 0.33 -0.2 -0.69 0.02
40341 BRD-K82484965 HT29 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.47
40643 BRD-K82484965 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.3 1.05 0.58
40883 BRD-K82484965 NEU 10 uM 24 h -0.27 -1.11 0.36 0.0 0.0 0.0
41204 BRD-K82484965 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41543 BRD-K82484965 SKB 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.93
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).