CMap Candidate Details

Structure:
CMap ID: C28666
Pert ID: BRD-K82677201
Compound Name: almitrine
Targets: ATP1A1
MoA: Neurotransmitter agonist
SMILES: Fc1ccc(cc1)C(N1CCN(CC1)c1nc(NCC=C)nc(NCC=C)n1)c1ccc(F)cc1
InchiKey: OBDOVFRMEYHSQB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
126409 BRD-K82677201 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126458 BRD-K82677201 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126484 BRD-K82677201 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126543 BRD-K82677201 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126585 BRD-K82677201 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134361 BRD-K82677201 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134383 BRD-K82677201 A549 0.74 uM 24 h -0.35 -1.47 1.43 -0.3 -1.02 0.61
134476 BRD-K82677201 HT29 0.03 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
134525 BRD-K82677201 HUVEC 0.03 uM 24 h -0.26 -1.06 0.26 0.25 0.87 0.17
134551 BRD-K82677201 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134611 BRD-K82677201 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134661 BRD-K82677201 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).